42 Results for "

Hosta plantaginea (Lam.) Aschers.

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "Hosta plantaginea (Lam.) Aschers." in MCE Product Catalog:

44
44 Cited Publications
Cat. No.: HY-14644
CAS No.: 541550-19-0
Purity:  99.80%
Synonyms: STA 5326; LAM-002A free base; AIT-101
Research Areas:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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44
44 Cited Publications
Cat. No.: HY-14644A
CAS No.: 870087-36-8
Purity:  99.83%
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
Research Areas:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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Cat. No.: HY-129467
CAS No.: 56472-29-8
Purity:  ≥98.0%
Synonyms: 2-Hydroxyoleic acid; 2-OHOA; LAM561
Target:  

Apoptosis

Research Areas:  

Cancer

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect .
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Cat. No.: HY-150229
CAS No.: 2803699-70-7
Purity:  98.84%
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .
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Cat. No.: HY-N3028
CAS No.: 108885-69-4
Taccalonolide B is microtubule stabilizer isolated from Tacca plantaginea, with antitumor activity. Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM .
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Cat. No.: HY-N8503
CAS No.: 147821-49-6
Niazimicin can be isolated from seeds and leaves of Moringa oleifera Lam. Niazimicin is thiocarbamate compound .
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Cat. No.: HY-N10842
CAS No.: 88140-31-2
6-Formyllimetin is a natural product isolated from the root bark of T. asiatica LAM .
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Cat. No.: HY-N10803
CAS No.: 15575-50-5
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin is a nature product that could be isolated form the root bark of Toddalia asiatica (L.) LAM .
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Cat. No.: HY-164915
CAS No.: 1218932-97-8
Target:  

Bacterial

Research Areas:  

Metabolic Disease

5-InoAz is an inositol analogue used as a metabolic probe for labeling the mycobacterial cell envelope. 5-InoAz integrates into cell envelope glycolipids [phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM), and lipoarabinomannan (LAM)] .
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Cat. No.: HY-N9097
CAS No.: 122001-32-5
Niazirin is an orally active antioxidant. Niazirin can be isolated from Moringa oleifera Lam. Niazirin reduces the production levels of ROS and MDA, while increasing the levels of superoxide dismutase SOD and glutathione peroxidase GPx. Niazirin also abolishes high glucose-induced PKCζ activation and inhibits Nox4 protein expression. Niazirin exhibits excellent free radical scavenging activity. Niazirin significantly inhibits high glucose-induced proliferation of vascular smooth muscle cells. Niazirin can be used in the research of diabetic atherosclerosis .
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Cat. No.: HY-N0080
CAS No.: 28095-18-3
Synonyms: Peucedanol methyl ether
Ulopterol is a coumarin isolated from the leaves of Toddalia asiatica (L.) Lam with potent antibacterial and antifungal activities .
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Cat. No.: HY-N12092
CAS No.: 2600799-45-7
PSX020 is the hosta plantaginea flower extract with antioxidant effects .
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Cat. No.: HY-14644B
CAS No.: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
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Cat. No.: HY-118362
CAS No.: 113579-07-0
Target:  

Bacterial

Research Areas:  

Infection

Netzahualcoyonol is a quinone methyl triterpene isolated from the roots of Salacia multiflora (Lam.) DC. Netzahualcoyonol exhibits antibacterial and anti-biofilm activities. Netzahualcoyonol inhibits Gram-positive bacteria (MIC=3.26–52 μM). Additionally, Netzahualcoyonol demonstrates cytotoxicity against Hep G2 cells (IC50 = 1.95 μM) but exhibits low toxicity towards Vero cells .
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Cat. No.: HY-N3652
CAS No.: 51593-96-5
Cuspidiol (compound 3) is a CH2Cl2 extract of Fagara zanthoxyloides Lam. Cuspidiol has antifungal and antioxidative activity .
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Cat. No.: HY-N9538
CAS No.: 55481-87-3
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin that can be found in Heracleum pyrenaicum Lam.
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Cat. No.: HY-N12351
CAS No.: 624739-20-4
Ellagic acid 4-O-α-L-arabinopyranoside, isolated from longan Dimocarpus longan Lour, syn. Euphoria longan Lam. has antioxidative activity .
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Cat. No.: HY-129467A
CAS No.: 1229114-68-4
Synonyms: 2-Hydroxyoleic acid sodium; 2-OHOA sodium; LAM561 sodium
Target:  

Apoptosis

Research Areas:  

Cancer

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) sodium is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid sodium has anti-tumor effect .
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Cat. No.: HY-139784
CAS No.: 182370-45-2
Synonyms: (R)-2-Hydroxyoleic acid; (R)-2-OHOA; (R)-LAM561
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities .
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Cat. No.: HY-129467R
CAS No.: 56472-29-8
Synonyms: 2-Hydroxyoleic acid (Standard); 2-OHOA (Standard); LAM561 (Standard)
Research Areas:  

Cancer

(Rac)-Idroxioleic acid (Standard) is the analytical standard of (Rac)-Idroxioleic acid. This product is intended for research and analytical applications. (Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect[1].
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